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Cancer Research Consortium of West Michigan

Adult Cancer Prevention and Cancer Control Clinical Trials

Cancer clinical trials are research studies for developing better ways of detecting, treating, and eventually preventing cancer. By taking part in a clinical trial, you are among the first to receive new research treatments before they are widely available. Your participation in a clinical trial will influence the future direction of cancer care.

If you are interested in participating in a clinical trial, consult with your physician. Please note: clinical trials are not risk free. Patients must explore the options that are best for their individuals needs with the help of their physician.

Provided drugs are underlined

For more information, call the CRCWM Main office at 616.391.1230 or 800.336.5079

Breast

Cancer Type: METASTATIC BREAST CANCER
Research Base: SWOG
Protocol: SWOG S1703

RANDOMIZED NON-INFERIORITY TRIAL COMPARING OVERALL SURVIVAL OF PATIENTS MONITORED WITH SERUM TUMOR MARKER DIRECTED DISEASE MONITORING (STMDDM) VERSUS USUAL CARE IN PATIENTS WITH METASTATIC HORMONE RECEPTOR POSITIVE BREAST CANCER

Cancer Type: ABC Companion
Research Base: Alliance
Protocol: Alliance A211601
EVALUATION OF MAMMOGRAPHIC BREAST DENSITY EFFECT OF ASPIRIN:
A COMPANION STUDY TO ALLIANCE STUDY A011502
Cancer Type: Breast Cancer
Research Base: Alliance
Protocol: Alliance A011202 Adjuvant

A RANDOMIZED PHASE III TRIAL COMPARING AXILLARY LYMPH NODE DISSECTION TO AXILLARY RADIATION IN BREAST CANCER PATIENTS (cT1-3 N1) WHO HAVE POSITIVE SENTINEL LYMPH NODE DISEASE AFTER NEOADJUVANT CHEMOTHERAPY

Cancer Type: Breast Cancer
Research Base: Alliance
Protocol: Alliance A221505 Adjuvant

RT CHARM: PHASE III RANDOMIZED TRIAL OF HYPOFRACTIONATED POST MASTECTOMY RADIATION WITH BREAST RECONSTRUCTION

Cancer Type: Breast Cancer
Research Base: Alliance
Protocol: Alliance A011104 CC Breast MRI

A011104: Effect of Preoperative Breast MRI on Surgical Outcomes, Costs and Quality of Life of Women with Breast Cancer

Cancer Type: Breast cancer
Research Base: Alliance
Protocol: Alliance A011401 CC Weight loss

Randomized Phase III Trial Evaluating the Role of Weight Loss in Adjuvant Treatment of Overweight and Obese Women with Early Breast Cancer

Cancer Type: Node Positive Her2 Negative Breast Cancer
Research Base: Alliance
Protocol: Alliance A011502 CC ASA

A RANDOMIZED PHASE III DOUBLE BLINDED PLACEBO CONTROLLED TRIAL OF ASPIRIN AS ADJUVANT THERAPY FOR NODE POSTIVE HER2 NEGATIVE BREAST CANCER: THE ABC TRIAL

Cancer Type: BREAST OR GYNECOLOGIC CANCER
Research Base: NRG
Protocol: NRG CC004 CC-Sexual Desire

PHASE II DOUBLE BLIND DOSE FINDING TRIAL OF BUPROPION VERSUS PLACEBO FOR SEXUAL DESIRE IN WOMEN WITH BREAST OR GYNECOLOGIC CANCER

Cancer Type: METASTATIC HER-2+ BREAST CANCER
Research Base: SWOG
Protocol: SWOG S1501 CC cardiac tox

S1501:  PROSPECTIVE EVALUATION OF CARVEDILOL IN PREVENTION OF CARDIAC TOXICITY IN PATIENTS WITH METASTATIC HER-2+ BREAST CANCER, PHASE III

Cancer Type: Cancer Control
Research Base: URCC
Protocol: URCC 16070 CC nausea

TREATMENT OF REFRACTORY NAUSEA

Cancer Type: Breast Cancer
Research Base: Wake Forest
Protocol: WF 97116 CC cog impair

WF 97116:  A Phase 3 Randomized Placebo Controlled Clinical Trial of Donepezil in Chemotherapy Exposed Breast Cancer Survivors with Cognitive Impairment

Cancer Control

Cancer Type: Breast Cancer
Research Base: Wake Forest
Protocol: WF 97116 CC cog impair

WF 97116:  A Phase 3 Randomized Placebo Controlled Clinical Trial of Donepezil in Chemotherapy Exposed Breast Cancer Survivors with Cognitive Impairment

Cancer Type: Breast Cancer
Research Base: Alliance
Protocol: Alliance A221505 Adjuvant

RT CHARM: PHASE III RANDOMIZED TRIAL OF HYPOFRACTIONATED POST MASTECTOMY RADIATION WITH BREAST RECONSTRUCTION

Cancer Type: Cancer Control
Research Base: URCC
Protocol: URCC 16070 CC nausea

TREATMENT OF REFRACTORY NAUSEA

Cancer Type: BREAST OR GYNECOLOGIC CANCER
Research Base: NRG
Protocol: NRG CC004 CC-Sexual Desire

PHASE II DOUBLE BLIND DOSE FINDING TRIAL OF BUPROPION VERSUS PLACEBO FOR SEXUAL DESIRE IN WOMEN WITH BREAST OR GYNECOLOGIC CANCER

Cancer Type: Lung Cancer
Research Base: Wake Forest
Protocol: WF- 20817CD

Implementation of Smoking Cessation Services (OaSiS)

Cancer Type: Young Adult Survivors
Research Base: Wake Forest
Protocol: WF 10217

Work Ability in Young Adult Survivors (WAYS)

Cancer Type: Screening
Research Base: ECOG-ACRIN
Protocol: EA1151 (TMIST)

Tomosynthesis Mammographic Imaging Screening Trial (TMIST)

Cancer Type: Lung Cancer
Research Base: Alliance
Protocol: Alliance A221504

A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PILOT STUDY OF AN ORAL, SELECTIVE PERIPHERAL OPIOID RECEPTOR ANTAGONIST IN ADVANCED NON-SMALL CELL LUNG CANCER (ADENOCARCINOMA)

Cancer Type: METASTATIC BREAST CANCER
Research Base: SWOG
Protocol: SWOG S1703

RANDOMIZED NON-INFERIORITY TRIAL COMPARING OVERALL SURVIVAL OF PATIENTS MONITORED WITH SERUM TUMOR MARKER DIRECTED DISEASE MONITORING (STMDDM) VERSUS USUAL CARE IN PATIENTS WITH METASTATIC HORMONE RECEPTOR POSITIVE BREAST CANCER

Cancer Type: Cancer Control - Nausea
Research Base: Alliance
Protocol: Alliance A221602

OLANZAPINEWITH ORWITHOUT FOSAPREPITANT FOR THE PREVENTION OF CHEMOTHERAPY INDUCED NAUSEA AND VOMITING (CINV) IN PATIENTS RECEIVING HIGHLY EMETOGENIC CHEMOTHERAPY (HEC): A PHASE III RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL

Cancer Type: Breast Cancer
Research Base: Wake Forest
Protocol: WF 97415

WF 97415:  Understanding and Predicting Breast Cancer Events after Treatment (UPBEAT)

Cancer Type: Multiple Cancer control
Research Base: SWOG
Protocol: SWOG S1714

A PROSPECTIVE OBSERVATIONAL COHORT STUDY TO DEVELOP A PREDICTIVE MODEL OF TAXANE-INDUCED PERIPHERAL NEUROPATHY IN CANCER PATIENTS

Cancer Type: CCDR
Research Base: Alliance
Protocol: Alliance A231602CD

Protocol Alliance A231602CD: Assessing Financial Difficulty in Patients with Blood Cancers

Cancer Type: METASTATIC HER-2+ BREAST CANCER
Research Base: SWOG
Protocol: SWOG S1501 CC cardiac tox

S1501:  PROSPECTIVE EVALUATION OF CARVEDILOL IN PREVENTION OF CARDIAC TOXICITY IN PATIENTS WITH METASTATIC HER-2+ BREAST CANCER, PHASE III

Cancer Type: Breast Cancer
Research Base: Alliance
Protocol: Alliance A011202 Adjuvant

A RANDOMIZED PHASE III TRIAL COMPARING AXILLARY LYMPH NODE DISSECTION TO AXILLARY RADIATION IN BREAST CANCER PATIENTS (cT1-3 N1) WHO HAVE POSITIVE SENTINEL LYMPH NODE DISEASE AFTER NEOADJUVANT CHEMOTHERAPY

Cancer Type: Node Positive Her2 Negative Breast Cancer
Research Base: Alliance
Protocol: Alliance A011502 CC ASA

A RANDOMIZED PHASE III DOUBLE BLINDED PLACEBO CONTROLLED TRIAL OF ASPIRIN AS ADJUVANT THERAPY FOR NODE POSTIVE HER2 NEGATIVE BREAST CANCER: THE ABC TRIAL

Cancer Type: Cognitive Impairment in Colorectal Cancer
Research Base: URCC
Protocol: URCC 16092

Phase II Study of Low-Dose Ibuprofen for Cognitive Impairment in Colorectal Cancer Patients Receiving Chemotherapy

Cancer Type: Breast cancer
Research Base: Alliance
Protocol: Alliance A011401 CC Weight loss

Randomized Phase III Trial Evaluating the Role of Weight Loss in Adjuvant Treatment of Overweight and Obese Women with Early Breast Cancer

Cancer Type: SCLC
Research Base: NRG
Protocol: NRG CC003

NRG CC003: Randomized Phase II/III Trial of Prophylactic Cranial Irradiation With or Without Hippocampal Avoidance for Small Cell Lung Cancer

Cancer Type: ABC Companion
Research Base: Alliance
Protocol: Alliance A211601
EVALUATION OF MAMMOGRAPHIC BREAST DENSITY EFFECT OF ASPIRIN:
A COMPANION STUDY TO ALLIANCE STUDY A011502
Cancer Type: CCDR
Research Base: Alliance
Protocol: Alliance A231601CD

Improving surgical care and outcomes in older cancer patients through implementation of an efficient pre-surgical toolkit (OPTI-surg)

Cancer Type: Cancer Control
Research Base: Wake Forest
Protocol: WF 1801

A Single Arm, Pilot Study of Ramipril for Preventing Radiation-Induced Cognitive Decline in Glioblastoma (GBM) Patients Receiving Brain Radiotherapy

Cancer Type: Cancer Control- stomatitis
Research Base: Alliance
Protocol: Alliance A221701

Phase III placebo-controlled trial to evaluate dexamethasone use for everolimus-induced oral stomatitis: prevention versus early treatment approaches

Cancer Type: Cancer-Related Fatigue
Research Base: URCC
Protocol: URCC 18007

Randomized Placebo-Controlled Trial of Bupropion for Cancer-Related Fatigue

Cancer Type: peripheral neuropathy in African American women
Research Base: ECOG-ACRIN
Protocol: EAZ171

Prospective validation trial of taxane therapy (docetaxel or weekly paclitaxel) and risk of chemotherapy-induced peripheral neuropathy in African American women

Cancer Type: Prostate Cancer
Research Base: Wake Forest
Protocol: WF - 1802

Influence of Primary Treatment for Prostate Cancer on Work Experience (PCW)

Cancer Type: Prostate Cancer
Research Base: NRG
Protocol: NRG CC007CD

“Increasing the Dose of Survivorship Care Planning in Prostate Cancer Survivors Who Receive Androgen Deprivation Therapy,” 

Cancer Type: Multisite - Screening
Research Base: NCI
Protocol: DCP-001
 

DCP-001: Use of a Clinical Trial Screening Tool to Address Cancer Health Disparities in the NCI Community Oncology Research Program (NCORP)

Cancer Type: Head and Neck
Research Base: Wake Forest
Protocol: WF 97115

WF 97115: A Phase III Prospective Randomized Trial of Acupuncture for Treatment of Radiation-Induced Xerostomia in Patients with Head and Neck Cancer. 

Cancer Type: Colorectal
Research Base: SWOG
Protocol: SWOG S0820

SWOG S0820: A Double Blind Placebo-Controlled Trial. Eflornithine vs Sulindac vs Elfornithine + Sulindac to prevent recurrence of high risk adenomas and second primary colorectal cancers. Stage 0-III Colon Cancer, Phase III. 

Gastrointestinal

Cancer Type: Colorectal
Research Base: SWOG
Protocol: SWOG S0820

SWOG S0820: A Double Blind Placebo-Controlled Trial. Eflornithine vs Sulindac vs Elfornithine + Sulindac to prevent recurrence of high risk adenomas and second primary colorectal cancers. Stage 0-III Colon Cancer, Phase III. 

Gynecologic

Cancer Type: BREAST OR GYNECOLOGIC CANCER
Research Base: NRG
Protocol: NRG CC004 CC-Sexual Desire

PHASE II DOUBLE BLIND DOSE FINDING TRIAL OF BUPROPION VERSUS PLACEBO FOR SEXUAL DESIRE IN WOMEN WITH BREAST OR GYNECOLOGIC CANCER

Head and Neck

Cancer Type: Head and Neck
Research Base: Wake Forest
Protocol: WF 97115

WF 97115: A Phase III Prospective Randomized Trial of Acupuncture for Treatment of Radiation-Induced Xerostomia in Patients with Head and Neck Cancer. 

Leukemia

Cancer Type: Myelodysplastic Syndromes
Research Base: ECOG-ACRIN
Protocol: NHLBI-MDS

The National Myelodysplastic Syndromes (MDS) Study

Lung

Cancer Type: Lung Cancer
Research Base: Wake Forest
Protocol: WF- 20817CD

Implementation of Smoking Cessation Services (OaSiS)

Cancer Type: Lung Cancer
Research Base: Alliance
Protocol: Alliance A221504

A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PILOT STUDY OF AN ORAL, SELECTIVE PERIPHERAL OPIOID RECEPTOR ANTAGONIST IN ADVANCED NON-SMALL CELL LUNG CANCER (ADENOCARCINOMA)

Cancer Type: SCLC
Research Base: NRG
Protocol: NRG CC003

NRG CC003: Randomized Phase II/III Trial of Prophylactic Cranial Irradiation With or Without Hippocampal Avoidance for Small Cell Lung Cancer

Multisite

Cancer Type: Multisite - Screening
Research Base: NCI
Protocol: DCP-001
 

DCP-001: Use of a Clinical Trial Screening Tool to Address Cancer Health Disparities in the NCI Community Oncology Research Program (NCORP)