Just in Time Protocols

Gastrointestinal

Protocol EAY191 - A6 [JIT]
Cancer Type: Biliary Tract

FOLFOX IN COMBINATION WITH BINIMETINIB AS 2ND LINE THERAPY FOR PATIENTS WITH ADVANCED BILIARY TRACT CANCERS WITH MAPK PATHWAY ALTERATIONS;: A COMBOMATCH TREATMENT TRIAL:

Please check out the rare protocol list to locate other studies within this disease site.

Genitourinary

Protocol Alliance A032302 [JIT}
Cancer Type: Prostate Cancer

Docetaxel Addition in Metastatic Castrate-Sensitive Prostate Cancer (ASPIRE)

Please check out the rare protocol list to locate other studies within this disease site.

Protocol EA8231 [JIT]
Cancer Type: Anti-PD(L)1-Resistant Advanced Urothelial Cancer

A Phase III Randomized Trial of Pembrolizumab in Combination with Sacituzumab Govitecan vs Standard of Care in Anti-PD(L)1-Resistant Advanced Urothelial Cancer

Please check out the rare protocol list to locate other studies within this disease site.

Please check out the rare protocol list to locate other studies within this disease site.

Gynecologic

Protocol EAY191-N5 [JIT]
Cancer Type: Gynecologic

EAY191-N5: A RANDOMIZED TRIAL OF NERATINIB, A PAN-ERBB INHIBITOR, ALONE OR IN COMBINATION WITH PALBOCICLIB, A CDK4/6 INHIBITOR, IN PATIENTS WITH HER2+ GYNECOLOGIC CANCERS AND OTHER SOLID TUMORS
A ComboMATCH Treatment Trial

Please check out the rare protocol list to locate other studies within this disease site.

Protocol EAY191-N4 [JIT]
Cancer Type: Gynecologic

A RANDOMIZED TRIAL OF SELUMETINIB AND OLAPARIB OR SELUMETINIB ALONE IN PATIENTS WITH RECURRENT OR PERSISTENT RAS PATHWAY MUTANT OVARIAN AND ENDOMETRIAL
CANCERS- A ComboMATCH Treatment Trial

Please check out the rare protocol list to locate other studies within this disease site.

Head and Neck

Protocol NRG HN010 JIT]
Cancer Type: Salivary Gland

A CONTROLLED, RANDOMIZED PHASE II TRIAL OF DOCETAXEL PLUS TRASTUZUMAB VERSUS ADO-TRASTUZUMAB EMTANSINE FOR RECURRENT, METASTATIC, OR TREATMENT-NAÏVE, UNRESECTABLE HER2-POSITIVE SALIVARY GLAND CANCER

Please check out the rare protocol list to locate other studies within this disease site.

Just in Time

Protocol Alliance A092001 [JIT]
Cancer Type: Peritoneal Mesothelioma

PHASE 2 RANDOMIZED TRIAL OF NEOADJUVANT OR PALLIATIVE CHEMOTHERAPY WITH OR WITHOUT IMMUNOTHERAPY FOR PERITONEAL MESOTHELIOMA

Please check out the rare protocol list to locate other studies within this disease site.

Protocol EAY191-N5 [JIT]
Cancer Type: Gynecologic

EAY191-N5: A RANDOMIZED TRIAL OF NERATINIB, A PAN-ERBB INHIBITOR, ALONE OR IN COMBINATION WITH PALBOCICLIB, A CDK4/6 INHIBITOR, IN PATIENTS WITH HER2+ GYNECOLOGIC CANCERS AND OTHER SOLID TUMORS
A ComboMATCH Treatment Trial

Please check out the rare protocol list to locate other studies within this disease site.

Protocol EA7222 [JIT]
Cancer Type: Sarcoma

A Randomized Phase III Trial of Doxorubicin + Pembrolizumab versus Doxorubicin Alone for the Treatment of Undifferentiated Pleomorphic Sarcoma (UPS) and Related Poorly Differentiated Sarcomas

Please check out the rare protocol list to locate other studies within this disease site.

Protocol EAY191-N4 [JIT]
Cancer Type: Gynecologic

A RANDOMIZED TRIAL OF SELUMETINIB AND OLAPARIB OR SELUMETINIB ALONE IN PATIENTS WITH RECURRENT OR PERSISTENT RAS PATHWAY MUTANT OVARIAN AND ENDOMETRIAL
CANCERS- A ComboMATCH Treatment Trial

Please check out the rare protocol list to locate other studies within this disease site.

Protocol EAY191 - A6 [JIT]
Cancer Type: Biliary Tract

FOLFOX IN COMBINATION WITH BINIMETINIB AS 2ND LINE THERAPY FOR PATIENTS WITH ADVANCED BILIARY TRACT CANCERS WITH MAPK PATHWAY ALTERATIONS;: A COMBOMATCH TREATMENT TRIAL:

Please check out the rare protocol list to locate other studies within this disease site.

Protocol EA8231 [JIT]
Cancer Type: Anti-PD(L)1-Resistant Advanced Urothelial Cancer

A Phase III Randomized Trial of Pembrolizumab in Combination with Sacituzumab Govitecan vs Standard of Care in Anti-PD(L)1-Resistant Advanced Urothelial Cancer

Protocol Alliance A032302 [JIT}
Cancer Type: Prostate Cancer

Docetaxel Addition in Metastatic Castrate-Sensitive Prostate Cancer (ASPIRE)

Please check out the rare protocol list to locate other studies within this disease site.

Protocol NRG HN010 JIT]
Cancer Type: Salivary Gland

A CONTROLLED, RANDOMIZED PHASE II TRIAL OF DOCETAXEL PLUS TRASTUZUMAB VERSUS ADO-TRASTUZUMAB EMTANSINE FOR RECURRENT, METASTATIC, OR TREATMENT-NAÏVE, UNRESECTABLE HER2-POSITIVE SALIVARY GLAND CANCER

Please check out the rare protocol list to locate other studies within this disease site.

Protocol SWOG S1800E [JIT]
Cancer Type: NSCLC

A Randomized Phase II/III Study of Docetaxel and Ramucirumab with or without Cemiplimab (REGN2810) for Participants Previously Treated with Platinum-based Chemotherapy and Immunotherapy for Stage IV or Recurrent Non-Small Cell Lung Cancer
(Lung-MAP Non-Matched Sub-Study)

Please check out the rare protocol list to locate other studies within this disease site.

Protocol EAY191-E5 [JIT]
Cancer Type: Solid Tumors

A Randomized Phase II Study of AMG 510 (Sotorasib) with or without Panitumumab in Advanced Solid Tumors: A ComboMATCH Treatment Trial

Please check out the rare protocol list to locate other studies within this disease site.

Lung

Protocol SWOG S1800E [JIT]
Cancer Type: NSCLC

A Randomized Phase II/III Study of Docetaxel and Ramucirumab with or without Cemiplimab (REGN2810) for Participants Previously Treated with Platinum-based Chemotherapy and Immunotherapy for Stage IV or Recurrent Non-Small Cell Lung Cancer
(Lung-MAP Non-Matched Sub-Study)

Please check out the rare protocol list to locate other studies within this disease site.

Multisite

Protocol EAY191-E5 [JIT]
Cancer Type: Solid Tumors

A Randomized Phase II Study of AMG 510 (Sotorasib) with or without Panitumumab in Advanced Solid Tumors: A ComboMATCH Treatment Trial

Please check out the rare protocol list to locate other studies within this disease site.

Sarcoma

Protocol EA7222 [JIT]
Cancer Type: Sarcoma

A Randomized Phase III Trial of Doxorubicin + Pembrolizumab versus Doxorubicin Alone for the Treatment of Undifferentiated Pleomorphic Sarcoma (UPS) and Related Poorly Differentiated Sarcomas

Please check out the rare protocol list to locate other studies within this disease site.

Cancer clinical trials are research studies for developing better ways of detecting, treating, and eventually preventing cancer. By taking part in a clinical trial, you are among the first to receive new research treatments before they are widely available. Your participation in a clinical trial will influence the future direction of cancer care.

If you are interested in participating in a clinical trial, consult with your physician. Please note: clinical trials are not risk free. Patients must explore the options that are best for their individuals needs with the help of their physician.